Mixed Reality vs Virtual Reality for Medical & Defence Training: The Complete 2025 Guide
- Ben K
- Nov 19
- 4 min read

Introduction
Training in high-risk environments, combat, aeromedical evacuation, emergency medicine, special operations, and frontline EMS requires realistic, hands-on practice with real equipment, real decision-making pressure, and true-to-life environments.
Until now, many organisations have adopted Virtual Reality (VR) simulation as an alternative to expensive live exercises. VR has its purpose and benefits, but its limitations are becoming increasingly apparent for medical training.
No ability to use real equipment
No tactile realism
Controller-based interfaces
Low-fidelity visuals
Poor skill transfer
Minimal multi-user realism
No actual muscle-memory development
Not suitable for mission-critical training
In 2025, the global training landscape is shifting from VR to Mixed Reality (MR), especially with the introduction of high-fidelity headsets like the Varjo XR-4.
This guide explains exactly why.
What Is Virtual Reality (VR)?
VR places the user inside a fully digital environment. Everything is computer-generated:
Digital hands
Digital equipment
Digital patients
Digital aircraft or vehicles
Digital lighting
Digital physics
VR relies on controllers or hand-model approximations, making it inherently limited for fine motor skills or the use of real-world equipment use.
Where VR works:
Introductory training
Cognitive walkthroughs
3D visualisation
Low-stakes simulations
Rehearsal of basic concepts
Procedures and decision making
Where VR fails:
Medical procedures requiring dexterity
CRM / Human Factors
Aircraft cabin constraints
Real equipment usage
Interoperability between different equipment and services
Care under fire
This is why organisations began searching for a more realistic alternative.
What Is Mixed Reality (MR)?
Mixed Reality blends the real and virtual worlds into a single training environment.
In MR:
Learners see their real hands
Learners use real equipment (medical tools, monitors, radios, weapons, manikins)
The headset overlays a photorealistic virtual environment around them
Real and virtual objects interact accurately
Multi-user teams operate in the same synthetic space
BlueRoom’s MR system uses:
Varjo XR-4 - the world’s most advanced MR headset
Human-eye resolution
Depth-accurate occlusion
Zero-motion-blur passthrough
HDR photorealism
Ultra-low latency
Perfect hand tracking
True fusion of virtual & real worlds
This enables trainees to perform actual tasks in a virtual environment:
Insert an airway
Control massive haemorrhage
Apply a tourniquet
Operate aircraft cabin equipment
Perform TCCC under fire
Use a real or simulated weapon
Treat a real manikin
Communicate using radios
Work inside virtual aircraft cabins
VR cannot do this.
Why Mixed Reality Is Replacing VR in 2025
Real Equipment, Real Hands and Real Muscle Memory
VR uses controllers, whereas mixed reality uses your real hands.
VR uses virtual objects whereas MR uses real objects.
This is essential for:
Paramedics
Doctors
Anaesthetics
Aeromedical teams
Combat medics
Critical care
Search and Rescue (SAR)
Police tactical medics
Special operations
In MR:
You feel the weight of tools.
You hear the click of equipment.
You manipulate real objects.
You perform tasks exactly as you would in real life.
In VR:
You are reliant on controllers or hand tracking
True Environmental Realism
MR use high-performance computers to ensure the highest quality environments which feel real:
Full-scale aircraft
Realistic lighting
Sound
Constrained environments
Terrain
Weather
Hazards
Airframe-Agnostic Reconfigurability (Unique to MR)
BlueRoom supports multiple aircraft, combat zones, pre-hospital scenes, hospitals and more. There is no need for physical environments or fuselage replicas.
Mixed Reality vs Virtual Reality: A Full Comparison Table
Feature | Mixed Reality (BlueRoom) | Virtual Reality |
Real hands | ✔ | ✘ (controllers) |
Real equipment | ✔ | ✘ |
Real manikins | ✔ | ✘ |
Real weapons | ✔ | ✘ |
Aircraft cabins | ✔ | ✘ |
Airframe-agnostic | ✔ | ✘ |
Multi-user realism | ✔ | Limited |
Real muscle memory | ✔ | ✘ |
Photorealistic passthrough | ✔ | ✘ |
Stress & biometric tracking | ✔ | ✘ |
Suitable for TCCC | ✔ | ✘ |
Suitable for aeromedical | ✔ | ✘ |
Team-based CRM | ✔ | ✘ |
Why Medical, Defence and EMS Organisations Are Transitioning to MR
Because MR solves the biggest training gaps:
✔ Limited access to aircraft
✔ Inability to rehearse in real environments
✔ High cost of live training
✔ Safety limitations
✔ Minimal realism in VR
✔ Reliance on digital controllers
✔ Inaccurate procedural practice
MR provides:
Deeper immersion
Better skill transfer
Higher student engagement
Safer high-stakes practice
Reduced need for aircraft
Better team-based rehearsal
More realistic medical scenarios
Custom mission rehearsal
Unlimited reconfigurability
BlueRoom: The World’s Most Advanced MR Training Ecosystem
BlueRoom offers:
✔ Mixed Reality Aeromedical Simulator
✔ Mixed Reality Full Mission Simulator (MR-FMS)
✔ Mixed Reality Tactical Combat Casualty Care
✔ BlueRoom Mission Control
✔ BlueRoom Biometrics
All powered by Varjo XR-4 and BlueRoom’s custom MR integration software.
Case Study: MR Aeromedical Training vs VR Aeromedical Training
Mixed Reality (BlueRoom)
Treat a real manikin in a virtual C-130J
Use real airway equipment
Use real monitors
Apply real tourniquets
Perform cabin workflow
Train CRM with multi-crew
Photorealistic aircraft cabin
Stress-inducing environmental cues
Virtual Reality
Controllers/hand tracking
Digital tools
Lower fidelity scenes
No physical constraints
No tactile realism
Case Study: MR TCCC vs VR TCCC
Mixed Reality (BlueRoom)
Real weapons
Real tactical procedures
Real medical tools
Real manikin
Smoke, lighting, explosions
Care under fire
HOT/WARM/COLD transitions
Multi-role teams
VR
Controller-based
Simplified scenes
No real tools
No weapon handling
No tactile realism
Requires controllers or hand tracking
When Should Organisations Use VR Instead of MR?
VR is appropriate for:
Early orientation and familiarisation
Low-stakes cognitive walkthroughs
Basic decision training
Procedure-based training
Basic concepts
But VR is not appropriate for:
Clinical skills
TCCC
Aeromedical workflows
Multi-crew aviation
Search and rescue
CRM
Specialist care
Care under fire
High-stakes simulation
Frequently Asked Questions
Is Mixed Reality better than VR for medical training?
Yes, if your objective is to practice fine motor skills using real equipment.
Can MR simulate an aircraft cabin?
Yes. MR can load full-scale airframes of fixed and rotary wing platforms.
Can VR simulate care under fire?
VR can simulate visuals; MR enables real-world tasks in a live-fire environment.
Is BlueRoom used by the Army?
Yes, BlueRoom is used by Royal Australian Air Force and Royal Netherlands Army along with others.
Does MR require a physical fuselage?
No, BlueRoom is airframe-agnostic and allows for training within any synthetic airframe using any equipment.
Which headset is best for MR?
Varjo XR-4 is used exclusively by BlueRoom.
Does MR provide better skill transfer than VR?
Yes, assuming the skill transfer required is a hard skill requiring the use of ones real hands and physical tools.
Is MR the Future of Simulation Training?
VR was an important step in training evolution, but 2025 belongs to Mixed Reality.
BlueRoom’s MR ecosystem enables:
Realism
Safety
True skill transfer
Multi-role coordination
Airframe-agnostic mission rehearsal
Cost-effective high-complexity training
The highest fidelity training available
For military, aeromedical, EMS, university and hospital environments, Mixed Reality is not a “nice-to-have”. It is a fundamental shift in training capability.



